How to prevent and manage hyperammonemic encephalopathies in valproate therapy

How to prevent and manage hyperammonemic encephalopathies in valproate therapy

Background: Valproic acid (VPA) has been increasingly shown to trigger hyperammonemic encephalopathies in patients suffering from urea cycle defects and in those receiving polypharmacy. Methods: We report on two cases of psychiatric inpatients with regular VPA intake who showed severe cognitive impa...

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Bibliographic Details
Main Authors: Marleen M M Mitschek, Thomas Vanicek, Jakob Unterholzner, Christoph Kraus, Ana Weidenauer, Angela Naderi-Heiden, Richard Frey, Leo R Silberbauer, Gregor Gryglewski, Konstantinos Papageorgiou, Dietmar Winkler, Markus Dold, Siegfried Kasper, Nicole Praschak-Rieder, Lucie Bartova
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Journal of Affective Disorders Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S266691532100113X

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http://www.sciencedirect.com/science/article/pii/S266691532100113X

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