Requirement of PML SUMO interacting motif for RNF4- or arsenic trioxide-induced degradation of nuclear PML isoforms.

Requirement of PML SUMO interacting motif for RNF4- or arsenic trioxide-induced degradation of nuclear PML isoforms.

PML, the organizer of nuclear bodies (NBs), is expressed in several isoforms designated PMLI to VII which differ in their C-terminal region due to alternative splicing of a single gene. This variability is important for the function of the different PML isoforms. PML NB formation requires the covale...

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Bibliographic Details
Main Authors: Mohamed Ali Maroui, Sabrina Kheddache-Atmane, Faten El Asmi, Laurent Dianoux, Muriel Aubry, Mounira K Chelbi-Alix
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3445614?pdf=render

Internet

http://europepmc.org/articles/PMC3445614?pdf=render

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