LDL subclass lipidomics in atherogenic dyslipidemia: effect of statin therapy on bioactive lipids and dense LDL[S]

LDL subclass lipidomics in atherogenic dyslipidemia: effect of statin therapy on bioactive lipids and dense LDL[S]

Atherogenic LDL particles are physicochemically and metabolically heterogeneous. Can bioactive lipid cargo differentiate LDL subclasses, and thus potential atherogenicity? What is the effect of statin treatment? Obese hypertriglyceridemic hypercholesterolemic males [n = 12; lipoprotein (a) <10 mg...

Full description

Bibliographic Details
Main Authors: M. John Chapman, Alexina Orsoni, Ricardo Tan, Natalie A. Mellett, Anh Nguyen, Paul Robillard, Philippe Giral, Patrice Thérond, Peter J. Meikle
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Journal of Lipid Research
Subjects:
metabolic syndrome
pitavastatin calcium
isopycnic density gradient ultracentrifugation
low density lipoprotein subclass heterogeneity
liquid chromatography electrospray ionization-tandem mass spectrometry
lipoprotein-associated phospholipase A2
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520436016

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520436016

Similar Items