A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome

Carpal tunnel syndrome (CTS) is caused by entrapment of the median nerve at the wrist. Here, Wiberg et al. perform a GWAS for CTS in the UK Biobank cohort and identify 16 genetic loci, and find a causal relationship between short stature and CTS risk using Mendelian randomisation.

Bibliographic Details
Main Authors: Akira Wiberg, Michael Ng, Annina B. Schmid, Robert W. Smillie, Georgios Baskozos, Michael V. Holmes, K. Künnapuu, R. Mägi, David L. Bennett, Dominic Furniss
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08993-6