Immunological observations and transcriptomic analysis of trimester‐specific full‐term placentas from three Zika virus‐infected women

Abstract Objectives Effects of Zika virus (ZIKV) infection on placental development during pregnancy are unclear. Methods Full‐term placentas from three women, each infected with ZIKV during specific pregnancy trimesters, were harvested for anatomic, immunologic and transcriptomic analysis. Results...

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Main Authors: Fok‐Moon Lum, Vipin Narang, Susan Hue, Jie Chen, Naomi McGovern, Ravisankar Rajarethinam, Jeslin JL Tan, Siti Naqiah Amrun, Yi‐Hao Chan, Cheryl YP Lee, Tze‐Kwang Chua, Wearn‐Xin Yee, Nicholas KW Yeo, Thiam‐Chye Tan, Xuan Liu, Sam Haldenby, Yee‐sin Leo, Florent Ginhoux, Jerry KY Chan, Julian Hiscox, Chia‐Yin Chong, Lisa FP Ng
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Clinical & Translational Immunology
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Online Access:https://doi.org/10.1002/cti2.1082