Mouse Strain-Dependent Difference Toward the Staphylococcus aureus Allergen Serine Protease-Like Protein D Reveals a Novel Regulator of IL-33

Mouse Strain-Dependent Difference Toward the Staphylococcus aureus Allergen Serine Protease-Like Protein D Reveals a Novel Regulator of IL-33

Staphylococcus aureus (S. aureus) can secrete a broad range of virulence factors, among which staphylococcal serine protease-like proteins (Spls) have been identified as bacterial allergens. The S. aureus allergen serine protease-like protein D (SplD) induces allergic asthma in C57BL/6J mice through...

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Bibliographic Details
Main Authors: Andrea R. Teufelberger, Sharon Van Nevel, Paco Hulpiau, Maria Nordengrün, Savvas N. Savvides, Sarah De Graeve, Srinivas Akula, Gabriele Holtappels, Natalie De Ruyck, Wim Declercq, Peter Vandenabeele, Lars Hellman, Barbara M. Bröker, Dmitri V. Krysko, Claus Bachert, Olga Krysko
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
allergy
asthma
IL-33
S. aureus
SplD
type 2 immunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.582044/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.582044/full

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