Role of connective tissue growth factor in vascular and renal damage associated with hypertension in rats. Interactions with angiotensin II

We have evaluated the role of connective tissue growth factor (CTGF) in vascular and renal damage associated with hypertension and possible interactions with angiotensin II (Ang II). Spontaneously hypertensive rats (SHR) were treated with either the Ang II receptor antagonist candesartan (C;2 mg/Kg...

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Bibliographic Details
Main Authors: Natalia de las Heras, Marta Ruiz-Ortega, Mónica Rupérez, David Sanz-Rosa, María Miana, Paloma Aragoncillo, Sergio Mezzano, Vicente Lahera, Jesús Egido, Victoria Cachofeiro
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2006-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2006.037