Abnormal Development of Dendrites in Adult-Born Rat Hippocampal Granule Cells Induced by Cyclophosphamide

Abnormal Development of Dendrites in Adult-Born Rat Hippocampal Granule Cells Induced by Cyclophosphamide

Although development of cognitive decline in cancer patients who receive chemotherapy is common, the underlying mechanism(s) remains to be identified. As abnormalities in adult hippocampal neurogenesis may serve as substrate for cognitive dysfunction, the present study examines the effect of cycloph...

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Bibliographic Details
Main Authors: Lin Wu, Dandan Guo, Qi Liu, Fei Gao, Xiaochen Wang, Xueying Song, Fuwu Wang, Ren-Zhi Zhan
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
adult neurogenesis
chemotherapy
cognition
dendrite
granule cell
hippocampus
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00171/full

Internet

http://journal.frontiersin.org/article/10.3389/fncel.2017.00171/full

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