Successful CRISPR/Cas9 mediated homologous recombination in a chicken cell line [version 2; referees: 2 approved, 1 approved with reservations]

Background: CRISPR/Cas9 system is becoming the dominant genome editing tool in a variety of organisms. CRISPR/Cas9 mediated knock out has been demonstrated both in chicken cell lines and in chicken germ cells that served to generate genetically modified birds. However, there is limited data about CR...

Full description

Bibliographic Details
Main Authors: Ekaterina Antonova, Olga Glazova, Anna Gaponova, Aykaz Eremyan, Svetlana Zvereva, Natalya Grebenkina, Natalya Volkova, Pavel Volchkov
Format: Article
Language:English
Published: F1000 Research Ltd 2018-05-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-238/v2