Combined use of Diane-35 and metformin improves the ovulation in the PCOS rat model possibly via regulating glycolysis pathway

Combined use of Diane-35 and metformin improves the ovulation in the PCOS rat model possibly via regulating glycolysis pathway

Abstract Background Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disease with unknown pathogenesis. However, the treatment of Diane-35 combined with metformin can improve the endocrine and ovulation of PCOS. In this study, we investigated the effects of Diane-35 combined wit...

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Bibliographic Details
Main Authors: Shun Zhang, Haoyan Tu, Jun Yao, Jianghua Le, Zhengxu Jiang, Qianqian Tang, Rongrong Zhang, Peng Huo, Xiaocan Lei
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Reproductive Biology and Endocrinology
Subjects:
PCOS
Diane-35
Metformin
Apoptosis
Glycolysis
SIRT1
Online Access:http://link.springer.com/article/10.1186/s12958-020-00613-z

Internet

http://link.springer.com/article/10.1186/s12958-020-00613-z

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