Complementary Roles of GCN5 and PCAF in Foxp3+ T-Regulatory Cells

Complementary Roles of GCN5 and PCAF in Foxp3+ T-Regulatory Cells

Functions of the GCN5-related N-acetyltransferase (GNAT) family of histone/protein acetyltransferases (HATs) in Foxp3+ T-regulatory (Treg) cells are unexplored, despite the general importance of these enzymes in cell biology. We now show that two prototypical GNAT family members, GCN5 (general contr...

Full description

Bibliographic Details
Main Authors: Yujie Liu, Chunrong Bao, Liqing Wang, Rongxiang Han, Ulf H. Beier, Tatiana Akimova, Philip A. Cole, Sharon Y. R. Dent, Wayne W. Hancock
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
acetyltransferase
Treg cells
epigenetics
transplantation
autoimmunity
anti-tumor immunity
acetylation
chromatin
Online Access:https://www.mdpi.com/2072-6694/11/4/554

Internet

https://www.mdpi.com/2072-6694/11/4/554

Similar Items