Prostaglandin E2-EP3 axis in fine-tuning excessive skin inflammation by restricting dendritic cell functions.

Prostaglandin E2 (PGE2) is produced in the skin and is suggested to play a role in the regulation of cutaneous immune homeostasis and responses. However, the multifaceted functions of PGE2 continue to elude our understanding, especially because of the multiplicity of PGE2 receptors--EP1, EP2, EP3, a...

Full description

Bibliographic Details
Main Authors: Noriko Shiraishi, Takashi Nomura, Hideaki Tanizaki, Saeko Nakajima, Shuh Narumiya, Yoshiki Miyachi, Yoshiki Tokura, Kenji Kabashima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23922752/?tool=EBI