An Adaptive Multivariate Two-Sample Test With Application to Microbiome Differential Abundance Analysis

An Adaptive Multivariate Two-Sample Test With Application to Microbiome Differential Abundance Analysis

Differential abundance analysis is a crucial task in many microbiome studies, where the central goal is to identify microbiome taxa associated with certain biological or clinical conditions. There are two different modes of microbiome differential abundance analysis: the individual-based univariate...

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Bibliographic Details
Main Authors: Kalins Banerjee, Ni Zhao, Arun Srinivasan, Lingzhou Xue, Steven D. Hicks, Frank A. Middleton, Rongling Wu, Xiang Zhan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Genetics
Subjects:
adaptive microbiome differential analysis (AMDA)
maximum mean discrepancy (MMD)
multivariate two-sample test
permutation
subset testing
taxa-set
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00350/full

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https://www.frontiersin.org/article/10.3389/fgene.2019.00350/full

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