Design of Mucoadhesive Nanostructured Polyelectrolyte Complexes Based on Chitosan and Hypromellose Phthalate for Metronidazole Delivery Intended to the Treatment of <i>Helicobacter pylori</i> Infections

Design of Mucoadhesive Nanostructured Polyelectrolyte Complexes Based on Chitosan and Hypromellose Phthalate for Metronidazole Delivery Intended to the Treatment of <i>Helicobacter pylori</i> Infections

Metronidazole (MT) is an important drug available for <i>Helicobacter pylori</i> infection treatment. However, in the past few years, this drug has presented effective reduction for infection control, one of the most important reasons is attributed to the reduction of retention time in t...

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Bibliographic Details
Main Authors: Maurício Palmeira Chaves de Souza, Nathalia Helena de Mattos, Liliane Neves Pedreiro, Fernanda Isadora Boni, Matheus Aparecido dos Santos Ramos, Taís Maria Bauab, Maria Palmira Daflon Gremião, Marlus Chorilli
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Pharmaceutics
Subjects:
mucoadhesive nanostructured polyelectrolyte complexes (nano PECs)
chitosan
design of experiments
adsorption isotherms
in vitro dissolution test
Online Access:https://www.mdpi.com/1999-4923/12/12/1211

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https://www.mdpi.com/1999-4923/12/12/1211

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