Infection of epididymal epithelial cells and leukocytes drives seminal shedding of Zika virus in a mouse model.

While primarily a mosquito-borne virus, Zika virus (ZIKV; genus Flavivirus in the Flaviviridae family) is capable of being sexually transmitted. Thirty to fifty percent of men with confirmed ZIKV infection shed ZIKV RNA in their semen, and prolonged viral RNA shedding in semen can occur for more tha...

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Bibliographic Details
Main Authors: Erin M McDonald, Nisha K Duggal, Jana M Ritter, Aaron C Brault
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6091970?pdf=render