The effect of acute moderate psychological stress on working memory-related neural activity is modulated by a genetic variation in catecholaminergic function in humans

The effect of acute moderate psychological stress on working memory-related neural activity is modulated by a genetic variation in catecholaminergic function in humans

Acute stress has an important impact on higher-order cognitive functions supported by the prefrontal cortex (PFC) such as working memory (WM). In rodents, such effects are mediated by stress-induced alterations in catecholaminergic signaling, but human data in support of this notion is lacking. A co...

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Bibliographic Details
Main Authors: Shaozheng eQin, Helena eCousijn, Mark eRijpkema, Jing eLuo, Barbara eFranke, Erno eHermans, Guillén eFernández
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Integrative Neuroscience
Subjects:
Catecholamines
Prefrontal Cortex
fMRI
stress
working memory
COMT
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnint.2012.00016/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnint.2012.00016/full

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