In Vitro Culture Duration does Not Impact the Ability of Encapsulated Choroid Plexus Transplants to Prevent Neurological Deficits in an Excitotoxin-Lesioned Rat Model of Huntington's Disease

Delivery of neurotrophic molecules to the CNS is a potential treatment strategy for preventing the neuronal loss accompanying many neurological disorders. Choroid plexus (CP) epithelial cells secrete a cocktail of neurotrophic factors, and encapsulated CP transplants are neuroprotective in animal mo...

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Bibliographic Details
Main Authors: Dwaine F. Emerich, Christopher G. Thanos
Format: Article
Language:English
Published: SAGE Publishing 2006-08-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000006783981657