Construction of à la carte QconCAT protein standards for multiplexed quantification of user-specified target proteins

Construction of à la carte QconCAT protein standards for multiplexed quantification of user-specified target proteins

Abstract Background QconCATs are quantitative concatamers for proteomic applications that yield stoichiometric quantities of sets of stable isotope-labelled internal standards. However, changing a QconCAT design, for example, to replace poorly performing peptide standards has been a protracted proce...

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Bibliographic Details
Main Authors: James Johnson, Victoria M. Harman, Catarina Franco, Edward Emmott, Nichola Rockliffe, Yaqi Sun, Lu-Ning Liu, Ayako Takemori, Nobuaki Takemori, Robert J. Beynon
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Biology
Subjects:
Synthetic biology
Standards
Absolute quantification
Stable isotopes
QconCAT
Quantitative proteomics
Online Access:https://doi.org/10.1186/s12915-021-01135-9

Internet

https://doi.org/10.1186/s12915-021-01135-9

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