High abundance of BDNF within glutamatergic presynapses of cultured hippocampal neurons

In the mammalian brain, the neurotrophin brain-derived neurotrophic factor (BDNF) has emerged as a key factor for synaptic refinement, plasticity and learning. Although BDNF-induced signaling cascades are well known, the spatial aspects of the synaptic BDNF localization remained unclear. Recent data...

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Bibliographic Details
Main Authors: Thomas eAndreska, Sarah eAufmkolk, Markus eSauer, Robert eBlum
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00107/full