Dual functionality of O-GlcNAc transferase is required for Drosophila development

Post-translational modification of intracellular proteins with O-linked N-acetylglucosamine (O-GlcNAc) catalysed by O-GlcNAc transferase (OGT) has been linked to regulation of diverse cellular functions. OGT possesses a C-terminal glycosyltransferase catalytic domain and N-terminal tetratricopeptide...

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Bibliographic Details
Main Authors: Daniel Mariappa, Xiaowei Zheng, Marianne Schimpl, Olawale Raimi, Andrew T. Ferenbach, H.-Arno J. Müller, Daan M. F. van Aalten
Format: Article
Language:English
Published: The Royal Society 2015-01-01
Series:Open Biology
Subjects:
hox
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.150234