CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion

CRISPR-based genetic elements can copy themselves across host genomes. Here the authors introduce CopyCatcher, a gene-drive related system for detecting and quantifying somatic gene conversion events.

Bibliographic Details
Main Authors: Zhiqian Li, Nimi Marcel, Sushil Devkota, Ankush Auradkar, Stephen M. Hedrick, Valentino M. Gantz, Ethan Bier
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22927-1