Up-regulation of Imp3 confers in vivo tumorigenicity on murine osteosarcoma cells.

Osteosarcoma is a high-grade malignant bone tumor that manifests ingravescent clinical behavior. The intrinsic events that confer malignant properties on osteosarcoma cells have remained unclear, however. We previously established two lines of mouse osteosarcoma cells: AX cells, which are able to fo...

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Bibliographic Details
Main Authors: Arisa Ueki, Takatsune Shimizu, Kenta Masuda, Sayaka I Yamaguchi, Tomoki Ishikawa, Eiji Sugihara, Nobuyuki Onishi, Shinji Kuninaka, Keita Miyoshi, Akihiro Muto, Yoshiaki Toyama, Kouji Banno, Daisuke Aoki, Hideyuki Saya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3511546?pdf=render