Human Gut-Commensalic Lactobacillus ruminis ATCC 25644 Displays Sortase-Assembled Surface Piliation: Phenotypic Characterization of Its Fimbrial Operon through In Silico Predictive Analysis and Recombinant Expression in Lactococcus lactis.

Sortase-dependent surface pili (or fimbriae) in Gram-positive bacteria are well documented as a key virulence factor for certain harmful opportunistic pathogens. However, it is only recently known that these multi-subunit protein appendages are also belonging to the "friendly" commensals a...

Full description

Bibliographic Details
Main Authors: Xia Yu, Annukka Jaatinen, Johanna Rintahaka, Ulla Hynönen, Outi Lyytinen, Ravi Kant, Silja Åvall-Jääskeläinen, Ingemar von Ossowski, Airi Palva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4692528?pdf=render