ZAR1 is a novel epigenetically inactivated tumour suppressor in lung cancer

ZAR1 is a novel epigenetically inactivated tumour suppressor in lung cancer

Abstract Background Lung cancer is the leading cause of cancer-related deaths with 1.8 million new cases each year and poor 5-year prognosis. Promoter hypermethylation of tumour suppressors leads to their inactivation and thereby can promote cancer development and progression. Results In this study,...

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Bibliographic Details
Main Authors: Antje M. Richter, Steffen Kiehl, Nicole Köger, Janina Breuer, Thorsten Stiewe, Reinhard H. Dammann
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Clinical Epigenetics
Subjects:
Lung cancer
ZAR1 (zygote arrest 1)
Tumour suppressor
DNA methylation
Epigenetics
Online Access:http://link.springer.com/article/10.1186/s13148-017-0360-4

Internet

http://link.springer.com/article/10.1186/s13148-017-0360-4

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