The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis.

Despite its multi-faceted role in neurodegenerative diseases, the physiological function of the prion protein (PrP) has remained elusive. On the basis of its evolutionary relationship to ZIP metal ion transporters, we considered that PrP may contribute to the morphogenetic reprogramming of cells und...

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Bibliographic Details
Main Authors: Mohadeseh Mehrabian, Dylan Brethour, Hansen Wang, Zhengrui Xi, Ekaterina Rogaeva, Gerold Schmitt-Ulms
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4546001?pdf=render