Diabetes-related changes in the protein composition and the biomechanical properties of human retinal vascular basement membranes.

Basement membranes (BMs) are specialized sheets of extracellular matrix that outline epithelial cell layers, muscle fibers, blood vessels, and peripheral nerves. A well-documented histological hallmark of progressing diabetes is a major increase in vascular BM thickness. In order to investigate whet...

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Bibliographic Details
Main Authors: Willi Halfter, Suzette Moes, Daphne O Asgeirsson, Kathrin Halfter, Philipp Oertle, Esther Melo Herraiz, Marija Plodinec, Paul Jenoe, Paul Bernhard Henrich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5746242?pdf=render