Pancreatic Cancer Organoids for Determining Sensitivity to Bromodomain and Extra-Terminal Inhibitors (BETi)

Pancreatic Cancer Organoids for Determining Sensitivity to Bromodomain and Extra-Terminal Inhibitors (BETi)

Pancreatic ductal adenocarcinoma (PDAC) is a heterogeneous disease, therefore stratification of patients is essential to predict their responses to therapies and to choose the best treatment. PDAC-derived organoids were produced from PDTX and Endoscopic Ultrasound-Guided Fine-Needle Aspiration (EUS-...

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Bibliographic Details
Main Authors: Benjamin Bian, Natalia Anahi Juiz, Odile Gayet, Martin Bigonnet, Nicolas Brandone, Julie Roques, Jérôme Cros, Nenghui Wang, Nelson Dusetti, Juan Iovanna
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Oncology
Subjects:
pancreatic cancer
organoids
c-MYC
NHWD-870
JQ1
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00475/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00475/full

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