Hopf bifurcation analysis of nonlinear HIV infection model and the effect of delayed immune response with drug therapies

Hopf bifurcation analysis of nonlinear HIV infection model and the effect of delayed immune response with drug therapies

Abstract A mathematical model of HIV infection with the combination of drug therapy including cytotoxic T-lymphocyte (CTL) and the antibody immune response is examined. The threshold value represented as the basic reproduction ratio R 0 $R_{0}$ is derived. This reveals that R 0 < 1 $R_{0} < 1$...

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Bibliographic Details
Main Authors: V. Geetha, S. Balamuralitharan
Format: Article
Language:English
Published: SpringerOpen 2020-08-01
Series:Boundary Value Problems
Subjects:
HIV Delay model
Local Stability
Hopf bifurcation
Online Access:http://link.springer.com/article/10.1186/s13661-020-01410-8

Internet

http://link.springer.com/article/10.1186/s13661-020-01410-8

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