A Clinical Rationale for Assessing the Impact of Childhood Sexual Abuse on Adjunctive Subcutaneous Esketamine for Treatment-Resistant Depression

A Clinical Rationale for Assessing the Impact of Childhood Sexual Abuse on Adjunctive Subcutaneous Esketamine for Treatment-Resistant Depression

Background: A history of child sexual abuse (CSA) is related to higher suicide rates and poor treatment outcomes in depressed adult patients. Twenty years after the first study investigating the effects of ketamine/esketamine on depression and suicide, there is a lack of data on the CSA effects on t...

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Bibliographic Details
Main Authors: Eduardo Jorge Muniz Magalhães, Luciana Maria Sarin, Lorena Catarina Del Sant, Ana Cecília Lucchese, Carolina Nakahira, Marco Aurélio Tuena, Camila Brito Puertas, Victor Augusto Rodovalho Fava, Rodrigo Simonini Delfino, Juliana Surjan, Matheus Souza Steglich, Matheus Ghossain Barbosa, Guilherme Abdo, José Alberto Del Porto, Charles B. Nemeroff, Hugo Cogo-Moreira, Acioly Luiz Tavares Lacerda, Andrea Feijo Mello
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Psychiatry
Subjects:
child sex abuse
treatment-resistant depression
esketamine
sex
directed acyclic graph
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.608499/full

Internet

https://www.frontiersin.org/articles/10.3389/fpsyt.2021.608499/full

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