Facile and Stereo-Selective Synthesis of UDP-α-D-xylose and UDP-β-L-arabinose Using UDP-Sugar Pyrophosphorylase

Facile and Stereo-Selective Synthesis of UDP-α-D-xylose and UDP-β-L-arabinose Using UDP-Sugar Pyrophosphorylase

A novel synthesis of nucleotide sugars was conducted to prepare UDP-α-D-xylose and UDP-β-L-arabinose without utilizing protection strategies or advanced purification techniques. Sugar-1-phosphates of D-xylose and L-arabinose were synthesized from their β-glycosylsulfonylhydrazides and evaluated as s...

Full description

Bibliographic Details
Main Authors: JiaJia Wang, Harmon Greenway, Shanshan Li, Mohui Wei, Samuel J. Polizzi, Peng G. Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Chemistry
Subjects:
UDP-xylose
UDP-arabinose
nucleotide sugar
chemo-enzymatic synthesis
UDP-sugar pyrophosphorylase
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2018.00163/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2018.00163/full

Similar Items