Limits to clinical trials in surgical areas

Randomized clinical trials are considered to be the gold standard of evidence-based medicine nowadays. However, it is important that we point out some limitations of randomized clinical trials relating to surgical interventions. There are limitations that affect the external and internal validity of...

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Bibliographic Details
Main Authors: Marco Kawamura Demange, Felipe Fregni
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2011-01-01
Series:Clinics
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011000100027