A Sir2-like protein participates in mycobacterial NHEJ.

In eukaryotic cells, repair of DNA double-strand breaks (DSBs) by the nonhomologous end-joining (NHEJ) pathway is critical for genome stability. In contrast to the complex eukaryotic repair system, bacterial NHEJ apparatus consists of only two proteins, Ku and a multifunctional DNA ligase (LigD), wh...

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Bibliographic Details
Main Authors: Zhongdao Li, Jikai Wen, Yaning Lin, Shihua Wang, Peng Xue, Zhiping Zhang, Ying Zhou, Xiao Wang, Li Sui, Li-Jun Bi, Xian-En Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3102665?pdf=render