The actin targeting compound Chondramide inhibits breast cancer metastasis via reduction of cellular contractility.

The actin targeting compound Chondramide inhibits breast cancer metastasis via reduction of cellular contractility.

<h4>Background</h4>A major player in the process of metastasis is the actin cytoskeleton as it forms key structures in both invasion mechanisms, mesenchymal and amoeboid migration. We tested the actin binding compound Chondramide as potential anti-metastatic agent.<h4>Methods</h...

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Bibliographic Details
Main Authors: Magdalena H Menhofer, Rebekka Kubisch, Laura Schreiner, Matthias Zorn, Florian Foerster, Rolf Mueller, Joachim O Raedler, Ernst Wagner, Angelika M Vollmar, Stefan Zahler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0112542

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https://doi.org/10.1371/journal.pone.0112542

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