Liposome-Encapsulated Bacillus Calmette–Guérin Cell Wall Skeleton Enhances Antitumor Efficiency for Bladder Cancer In Vitro and In Vivo via Induction of AMP-Activated Protein Kinase

Liposome-Encapsulated Bacillus Calmette–Guérin Cell Wall Skeleton Enhances Antitumor Efficiency for Bladder Cancer In Vitro and In Vivo via Induction of AMP-Activated Protein Kinase

The <i>Mycobacterium</i> Bacillus Calmette-Guérin cell wall skeleton (BCG-CWS), the main immune active center of BCG, is a potent candidate non-infectious immunotherapeutic drug and an alternative to live BCG for use against urothelial carcinoma. However, its application in anticancer th...

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Bibliographic Details
Main Authors: Young Mi Whang, Da Hyeon Yoon, Gwang Yong Hwang, Hoyub Yoon, Serk In Park, Young Wook Choi, In Ho Chang
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
AMP activated protein kinase (AMPK)
reactive oxygen species (ROS)
endoplasmic reticulum (ER) stress
bladder cancer
orthotopic bladder cancer mouse model
BCG-CWS drug-delivery system
Online Access:https://www.mdpi.com/2072-6694/12/12/3679

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https://www.mdpi.com/2072-6694/12/12/3679

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