Rules for resolving Mendelian inconsistencies in nuclear pedigrees typed for two-allele markers.

Gene-mapping studies, regularly, rely on examination for Mendelian transmission of marker alleles in a pedigree as a way of screening for genotyping errors and mutations. For analysis of family data sets, it is, usually, necessary to resolve or remove the genotyping errors prior to consideration. At...

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Bibliographic Details
Main Authors: Sajjad Ahmad Khan, Sadaf Manzoor, Alamgir, Amjad Ali, Dost Muhammad Khan, Umair Khalil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5333839?pdf=render