Hydroxysafflor Yellow A Protects Against Myocardial Ischemia/Reperfusion Injury via Suppressing NLRP3 Inflammasome and Activating Autophagy

Hydroxysafflor Yellow A Protects Against Myocardial Ischemia/Reperfusion Injury via Suppressing NLRP3 Inflammasome and Activating Autophagy

Myocardial ischemia/reperfusion (MI/R) injury is a serious threat to human health. Hydroxysafflor yellow A (HSYA), the main water-soluble ingredient extracted from Carthami flos (Carthamus tinctorius L.), has therapeutic potential for treating MI/R injury. However, the mechanisms of HSYA−mediated pr...

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Bibliographic Details
Main Authors: Jingxue Ye, Shan Lu, Min Wang, Wenxiu Ge, Haitao Liu, Yaodong Qi, Jianhua Fu, Qiong Zhang, Bengang Zhang, Guibo Sun, Xiaobo Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pharmacology
Subjects:
myocardial ischemia reperfusion injury
hydroxysafflor yellow A
NLRP3
autophagy
AMPK
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01170/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.01170/full

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