Tumour Microenvironment and Immune Evasion in EGFR Addicted NSCLC: Hurdles and Possibilities

Tumour Microenvironment and Immune Evasion in EGFR Addicted NSCLC: Hurdles and Possibilities

In the last few years, the treatment strategy in Non-Small Cell Lung Cancer (NSCLC) patients has been heavily modified by the introduction of the immune-checkpoint inhibitors. Anti-programmed cell death 1/programmed cell death ligand 1 (PD-1/PD-L1) therapy has improved both progression-free and the...

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Bibliographic Details
Main Authors: Antonio Santaniello, Fabiana Napolitano, Alberto Servetto, Pietro De Placido, Nicola Silvestris, Cataldo Bianco, Luigi Formisano, Roberto Bianco
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cancers
Subjects:
immune checkpoint inhibitors
ICI
EGFR mutation
NSCLC
angiogenesis
TKI
tumour microenvironment
TME
tumour mutational burden
TMB
Online Access:https://www.mdpi.com/2072-6694/11/10/1419

Internet

https://www.mdpi.com/2072-6694/11/10/1419

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