Enhancing immunogenicity of HPV16 E7 DNA vaccine by conjugating codon-optimized GM-CSF to HPV16 E7 DNA

Objective: To generate immunity against human papillomavirus (HPV), the use of a recombinant DNA vaccine to carry an appropriate target gene is a promising and cost-effective approach. Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a potent immunomodulatory cytokine that enhances the e...

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Bibliographic Details
Main Authors: Yi-Pin Chen, Chu-Chi Lin, Yu-Xin Xie, Chia-Yuan Chen, J. Timothy Qiu
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Taiwanese Journal of Obstetrics & Gynecology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1028455921001327