CRISPR deletion of MIEN1 in breast cancer cells.

Migration and Invasion Enhancer (MIEN1) is an oncogene which is involved in facilitating motility of cancer cells through actin dynamics and gene expression. Increased MIEN1 expression in many types of tumors leads to disease progression and metastatic propensity. It is unclear precisely how MIEN1 i...

Full description

Bibliographic Details
Main Authors: Timothy Van Treuren, Jamboor K Vishwanatha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6171864?pdf=render