Notch Signaling Regulates Muscle Stem Cell Homeostasis and Regeneration in a Teleost Fish

Muscle regeneration is mediated by the activity of resident muscle satellite cells (muSCs) that express Pax7. In mouse Notch signaling regulates muSCs during quiescence and promotes muSC proliferation in regeneration. It is unclear if these roles of Notch in regulating muSC biology are conserved acr...

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Bibliographic Details
Main Authors: Sami H. A. Sultan, Carlene Dyer, Robert D. Knight
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.726281/full