Migration and invasion of NSCLC suppressed by the downregulation of Src/focal adhesion kinase using single, double and tetra domain anti- CEACAM6 antibodies

Migration and invasion of NSCLC suppressed by the downregulation of Src/focal adhesion kinase using single, double and tetra domain anti- CEACAM6 antibodies

Carcinoembryonic antigen-related cell adhesion molecules 6 (CEACAM6) is a cell adhesion receptor. Expression of CEACAM6 in non-small cell lung cancer (NSCLC) associated with tumor progression and metastatic condition via Src/FAK signaling pathway. We established three anti-CEACAM6 antibodies with va...

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Bibliographic Details
Main Authors: Shang-Jung Wu, Arivajiagane Arundhathi, Hsiang-Ching Wang, Chiao-Yun Chen, Tsai-Mu Cheng, Shyng-Shiou F. Yuan, Yun-Ming Wang
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Translational Oncology
Subjects:
Non-small cell lung cancer
Anti-CEACAM6
Antibodies
Src/FAK signaling
Migration and invasion
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523321000498

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http://www.sciencedirect.com/science/article/pii/S1936523321000498

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