Matrine treatment reduces retinal ganglion cell apoptosis in experimental optic neuritis

Abstract Inflammatory demyelination and axonal injury of the optic nerve are hallmarks of optic neuritis (ON), which often occurs in multiple sclerosis and is a major cause of visual disturbance in young adults. Although a high dose of corticosteroids can promote visual recovery, it cannot prevent p...

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Bibliographic Details
Main Authors: Jian Kang, Shuqing Liu, Yifan Song, Yaojuan Chu, Mengru Wang, Yamin Shi, Fengyan Zhang, Lin Zhu
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89086-7