Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival

Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival

Mg2+ regulates many physiological processes and signalling pathways. However, little is known about the mechanisms underlying the organismal balance of Mg2+. Capitalizing on a set of newly generated mouse models, we provide an integrated mechanistic model of the regulation of organismal Mg2+ balance...

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Bibliographic Details
Main Authors: Vladimir Chubanov, Silvia Ferioli, Annika Wisnowsky, David G Simmons, Christin Leitzinger, Claudia Einer, Wenke Jonas, Yuriy Shymkiv, Harald Bartsch, Attila Braun, Banu Akdogan, Lorenz Mittermeier, Ludmila Sytik, Friedrich Torben, Vindi Jurinovic, Emiel PC van der Vorst, Christian Weber, Önder A Yildirim, Karl Sotlar, Annette Schürmann, Susanna Zierler, Hans Zischka, Alexey G Ryazanov, Thomas Gudermann
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-12-01
Series:eLife
Subjects:
magnesium
intestine
kidney
placenta
trophoblast stem cells
longevity
Online Access:https://elifesciences.org/articles/20914

Internet

https://elifesciences.org/articles/20914

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