Obesity Suppresses Estrogen Receptor Beta Expression in Breast Cancer Cells via a HER2-Mediated Pathway.

Obesity is associated with a worse breast cancer prognosis, while greater breast tumor estrogen receptor beta (ERβ) expression is correlated with improved therapy response and survival. The objective of this study was to determine the impact of obesity on breast cancer cell ERβ expression, which is...

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Bibliographic Details
Main Authors: Laura W Bowers, Megan Wiese, Andrew J Brenner, Emily L Rossi, Rajeshwar R Tekmal, Stephen D Hursting, Linda A deGraffenried
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4692402?pdf=render