Survival of glucose phosphate isomerase null somatic cells and germ cells in adult mouse chimaeras
The mouse Gpi1 gene encodes the glycolytic enzyme glucose phosphate isomerase. Homozygous Gpi1−/− null mouse embryos die but a previous study showed that some homozygous Gpi1−/− null cells survived when combined with wild-type cells in fetal chimaeras. One adult female Gpi1−/−↔Gpi1c/c chimaera with...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2016-05-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/5/5/596 |