FcεRI-α siRNA Inhibits the Antigen-Induced Activation of Mast Cells

FcεRI, The high affinity receptor for IgE plays a critical role in triggering the allergic reactions. It is responsible for inducing mast cell degranulation and deliberation of allergy mediators when it is aggregated by allergen and IgE complexes. FcεRI on the mast cells consists of three subunits;...

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Bibliographic Details
Main Authors: Reza Safaralizadeh, Zahra-Soheila Soheili, Abdolkhaleg Deezagi, Zahra Pourpak, Shahram Samiei, Mostafa Moin
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2009-12-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/254