An Innovative Protocol for Metaproteomic Analyses of Microbial Pathogens in Cystic Fibrosis Sputum

An Innovative Protocol for Metaproteomic Analyses of Microbial Pathogens in Cystic Fibrosis Sputum

Hallmarks of cystic fibrosis (CF) are increased viscosity of mucus and impaired mucociliary clearance within the airways due to mutations of the cystic fibrosis conductance regulator gene. This facilitates the colonization of the lung by microbial pathogens and the concomitant establishment of chron...

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Bibliographic Details
Main Authors: Alexander C. Graf, Johanna Striesow, Jan Pané-Farré, Thomas Sura, Martina Wurster, Michael Lalk, Dietmar H. Pieper, Dörte Becher, Barbara C. Kahl, Katharina Riedel
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
cystic fibrosis
sputum
microbial community
microbiome
16S sequencing
metaproteomics
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.724569/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2021.724569/full

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