Advancing paternal age is associated with deficits in social and exploratory behaviors in the offspring: a mouse model.

Advancing paternal age is associated with deficits in social and exploratory behaviors in the offspring: a mouse model.

BACKGROUND: Accumulating evidence from epidemiological research has demonstrated an association between advanced paternal age and risk for several psychiatric disorders including autism, schizophrenia and early-onset bipolar disorder. In order to establish causality, this study used an animal model...

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Bibliographic Details
Main Authors: Rebecca G Smith, Rachel L Kember, Jonathan Mill, Cathy Fernandes, Leonard C Schalkwyk, Joseph D Buxbaum, Abraham Reichenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2794376?pdf=render

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http://europepmc.org/articles/PMC2794376?pdf=render

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