<i>N</i>-Ethyl-<i>n</i>-Nitrosourea Induced Leukaemia in a Mouse Model through Upregulation of Vascular Endothelial Growth Factor and Evading Apoptosis

<i>N</i>-Ethyl-<i>n</i>-Nitrosourea Induced Leukaemia in a Mouse Model through Upregulation of Vascular Endothelial Growth Factor and Evading Apoptosis

Chemical carcinogens are commonly used to investigate the biology and prognoses of various cancers. This study investigated the mechanism of leukaemogenic effects of <i>n</i>-ethyl-<i>n</i>-nitrosourea (ENU) in a mouse model. A total of 14 3-week-old male Institute of Cancer...

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Bibliographic Details
Main Authors: Abdullahi Aliyu, Mohd Rosly Shaari, Nurul Syahirah Ahmad Sayuti, Mohd Farhan Hanif Reduan, Shanmugavelu Sithambaram, Mustapha Mohamed Noordin, Khozirah Shaari, Hazilawati Hamzah
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
leukaemia
<i>n</i>-ethyl-<i>n</i>-nitrosourea
blast cells
angiogenesis
vegf
apoptosis
bcl2
Online Access:https://www.mdpi.com/2072-6694/12/3/678

Internet

https://www.mdpi.com/2072-6694/12/3/678

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