Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity

Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity

Bacteria use CRISPR-Cas systems to protect themselves against viral infections. Here, Watson et al. show that a type I CRISPR-Cas system can induce abortive viral infection, where infected cells do not survive but viral propagation is decreased, thus protecting the bacterial population.

Bibliographic Details
Main Authors: Bridget N. J. Watson, Reuben B. Vercoe, George P. C. Salmond, Edze R. Westra, Raymond H. J Staals, Peter C. Fineran
Format: Article
Language:English
Published: Nature Publishing Group 2019-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13445-2

Internet

https://doi.org/10.1038/s41467-019-13445-2

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